Fatal Implant-Associated Lymphoma After Buttock Enhancement

By Marilynn Larkin

March 06, 2019

The first reported case of implant-associated anaplastic large-cell lymphoma (ALCL) outside the breast is "uniquely unfortunate" and has prompted new concern about the risks of ALCL with textured silicone implants used elsewhere in the body, say experts.

"It is imperative that all physicians recognize that patients with textured silicone implants other than breast implants may also be at risk of ALCL," says Daniel J. Gould, MD, PhD, from the Keck Hospital of the University of Southern California, Los Angeles, and colleagues, who reported the case.

Despite aggressive chemotherapy and resuscitation, the patient died of renal and respiratory failure several months later.

The number of reported cases of BIA-ALCL has been growing steadily worldwide. On February 6, the US Food and Drug Administration (FDA) said a total of 660 medical device reports (MDRs) had been received on BIA-ALCL cases in the US since 2010. In Europe, French surgeons have called a moratorium on the use of textured breast implants, with prophylactic implant removal in concerned patients.

PACI Institute